Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136825 | 0.79 | GNAI3 (0.46) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| SCHEMBL505101 | 0.77 | GPR119 (0.37) | CHRM2CHRM1CHRM3DPP4DPP7 | |
| SCHEMBL1517004 | 0.77 | GNAI3 (0.44) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL1136694 | 0.77 | GNAI3 (0.48) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL1136691 | 0.77 | GNAI3 (0.48) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| SCHEMBL112479 | 0.77 | GNAI3 (0.44) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| SCHEMBL4757619 | 0.76 | GAA (0.53) | CHRM1GAAALDH1A1TSHR | |
| SCHEMBL10128163 | 0.75 | GNAI3 (0.43) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3286216 | 0.75 | GNAI3 (0.47) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL4120587 | 0.75 | GNAI3 (0.47) | GNAI3GNAO1GNAI1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |