Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042347 | 0.89 | — | — | |
| SCHEMBL4051297 | 0.85 | CTSK (0.37) | CTSK | |
| SCHEMBL4042619 | 0.83 | HPGD (0.33) | — | |
| SCHEMBL4045319 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL4051828 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL4044554 | 0.81 | CTSV (0.32) | CTSK | |
| SCHEMBL4048747 | 0.81 | CTSK (0.39) | CTSK | |
| SCHEMBL4043270 | 0.80 | CTSK (0.32) | CTSK | |
| SCHEMBL4048571 | 0.80 | MEN1 (0.32) | — | |
| SCHEMBL4048915 | 0.80 | SMYD3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |