SCHEMBL4048113

SCHEMBL4048113

Oc1cc(Br)c(Br)cc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.48
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALOX12 P18054 1/20 0.37
AHR P35869 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35
CYP2C19 P33261 1/20 0.35
SNCA P37840 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48448 0.93 ALOX15 (0.53) ALOX15CA1CA2CA4CA6
SCHEMBL69493 0.89 ALOX15 (0.50) ALOX15CA1CA2CA4CA6
SCHEMBL67808 0.85 ALOX15 (0.46) ALOX15CA1CA2CA4CA6
SCHEMBL29878415 0.85 ALOX15 (0.46) ALOX15CA1CA2CA4CA6
SCHEMBL13672134 0.80 ALOX15 (0.50) ALOX15CYP3A4TSHRTDP1ALOX12
Methoxymethane SCHEMBL10964239 0.80 ALOX15 (0.43) ALOX15CA2CA4CYP3A4TSHR
Triclofenol SCHEMBL11818770 0.80 HSD17B10 (0.64) ALOX15CA1CA2CA4CA6
SCHEMBL2367985 0.76 ALOX15 (0.46) ALOX15CA1CA2CA4CA6
SCHEMBL2368577 0.76 ALOX15 (0.46) ALOX15CA1CA2CA4CA6
SCHEMBL12484114 0.76 ALOX15 (0.46) ALOX15CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333485-A Linear polyphosphazene halogen flame-retardant toughened modified glass fiber reinforced polyamide 6/polyamide 66 composite material 清华大学 2023-06-27 CN claimed
CN-112946121-B Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2023-04-11 CN claimed
CN-112946121-A Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2021-06-11 CN claimed
CN-106957218-B Solid-phase synthesis method and application of polybrominated diphenyl ether monomer 山东省分析测试中心 2020-07-24 CN claimed
CN-106957218-A A kind of solid phase synthesis process of PBBs ether monomer and application 山东省分析测试中心 2017-07-18 CN claimed
CN-116333485-A Linear polyphosphazene halogen flame-retardant toughened modified glass fiber reinforced polyamide 6/polyamide 66 composite material 清华大学 2023-06-27 CN disclosed
CN-112946121-B Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2023-04-11 CN disclosed
CN-112946121-A Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2021-06-11 CN disclosed
CN-106957218-B Solid-phase synthesis method and application of polybrominated diphenyl ether monomer 山东省分析测试中心 2020-07-24 CN disclosed
CN-106957218-A A kind of solid phase synthesis process of PBBs ether monomer and application 山东省分析测试中心 2017-07-18 CN disclosed
CN-104860799-B A kind of microwave synthesis method of PBBs ether monomer 山东省分析测试中心 2016-10-12 CN disclosed
CN-104860799-A Microwave synthesis method of polybrominated diphenyl ether monomer SHANDONG ANALYSIS & TEST CT 2015-08-26 CN disclosed
CN-1263882-A Method for preparing fluorine-substituted aromatic compound MITSUI CHEMICALS INC (JP) 2000-08-23 CN disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0240459-A1 Curable compositions CIBA-GEIGY AG (CH) 1987-10-07 EP disclosed
US-4588835-A Process for preparing alkoxyphenols OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1986-05-13 US disclosed
US-4460716-A Coated sand composition and method for producing same SUMITOMO DUREZ COMPANY, LTD. (JP) 1984-07-17 US disclosed
US-4115364-A MELT SPINNING WITH A THERMOPLASTIC NYLON, CURING, REACTING WITH UREA COMPOUND NIPPON KYNOL INCORPORATED (JP) 1978-09-19 US disclosed
US-4005151-A Process for producing polyhalogenated phenols HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-25 US disclosed
US-3961123-A SULFONATED NOVOLAKS CONTAINING METAL ATOMS KANEBO, LTD. (JA) 1976-06-01 US disclosed