Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741206 | 1.00 | MAPT (0.68) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL6742277 | 0.98 | MAPT (0.66) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL6742274 | 0.98 | MAPT (0.66) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL1189176 | 0.89 | SIGMAR1 (0.57) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL1190075 | 0.89 | SIGMAR1 (0.57) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL17069524 | 0.88 | MAPT (0.70) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL17426061 | 0.88 | MAPT (0.70) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL17069523 | 0.88 | MAPT (0.70) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL17426063 | 0.88 | MAPT (0.70) | MAPTSIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL25154402 | 0.86 | MAPT (0.54) | MAPTSIGMAR1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461315-A4 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2005-06-01 | — | — | EP | claimed |
| US-6852865-B2 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-02-08 | — | — | US | claimed |
| EP-1461315-A2 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2004-09-29 | — | — | EP | claimed |
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. | 2003-08-28 | — | — | US | claimed |
| WO-2003050154-A2 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2003-06-19 | — | — | WO | claimed |
| CN-104428331-B | Active energy beam polymer resin composition and the laminated body for using the resin combination | 东洋油墨SC控股株式会社 | 2019-02-15 | — | — | CN | disclosed |
| CN-104428331-A | Active energy ray-polymerizable resin composition and laminate obtained using resin composition | TOYO INK SC HOLDINGS CO LTD | 2015-03-18 | — | — | CN | disclosed |
| EP-1461315-B1 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1461315-B1 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2009-07-29 | — | — | EP | disclosed |
| US-6852865-B2 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| US-20040131551-A1 | Enhanced relaxivity monomeric and multimeric compounds | BRISTOL-MYERS SQUIBB COMPANY | 2004-07-08 | — | — | US | disclosed |
| US-6693190-B1 | TETRAAZACYCLODODECANE MACROCYCLE DERIVATIVES INCLUDING METAL COMPLEXES; MAGNETIC RESONANCE IMAGING AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2004-02-17 | — | — | US | disclosed |
| EP-0883610-B1 | PROCESS FOR PREPARING 1,4,7,10-TETRAAZACYCLODODECANE AND ITS DERIVATIVES | SCHERING AG (DE) | 2000-07-12 | — | — | EP | disclosed |
| CN-1211975-A | Process for preparing 1,4,7,10-tetraazacyclododecane and its derivatives | SCHERING AG (DE) | 1999-03-24 | — | — | CN | disclosed |
| EP-0883610-A1 | PROCESS FOR PREPARING 1,4,7,10-TETRAAZACYCLODODECANE AND ITS DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0872479-A1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO S.p.A. (IT) | 1998-10-21 | — | — | EP | disclosed |
| US-5744616-A | CYCLOTETRAMERIZATION OF A BENZYLAZIRIDINE DERIVATIVE | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| WO-1997031905-A1 | PROCESS FOR PREPARING 1,4,7,10-TETRAAZACYCLODODECANE AND ITS DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-04 | — | — | WO | disclosed |
| CN-1128534-A | Monomeric and multimeric compounds with improved relaxivity | BRACCO INT BV (NL) | 1996-08-07 | — | — | CN | disclosed |
| WO-1995031444-A1 | ENHANCED RELAXIVITY MONOMERIC AND MULTIMERIC COMPOUNDS | BRACCO INTERNATIONAL B.V. (NL) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040131551-A1 | Enhanced relaxivity monomeric and multimeric compounds | H1-2, H1-0, H1-3 | MAPT 2852/4885SIGMAR1 1104/4885PDK1 3636/4885 |
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | LOX, CA9, LPO | MAPT 4734/4885SIGMAR1 2604/4885PDK1 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.