Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | MIF | P14174 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3273967 | 0.94 | HSD17B3 (0.53) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL15961994 | 0.83 | HSD17B3 (0.63) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL19480350 | 0.78 | HSD17B3 (0.56) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL9436011 | 0.78 | MIF (0.60) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL620973 | 0.77 | HPGD (0.55) | ESR2KDM4EGLAGAAMAPT | |
| SCHEMBL10794401 | 0.77 | HSD17B3 (0.64) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL5296804 | 0.77 | HSD17B3 (0.68) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL3273965 | 0.75 | STS (0.48) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL10789981 | 0.74 | HSD17B3 (0.64) | HSD17B3ESR2MIFMEN1KMT2A | |
| SCHEMBL1607902 | 0.74 | HSD17B3 (0.64) | HSD17B3ESR2MIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |