SCHEMBL4048269

SCHEMBL4048269

COc1c(F)c(O)c(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129794 0.95 TDP1 (0.36) HSD17B10TDP1CYP3A4MAPTPDE4A
SCHEMBL21103403 0.87 HSD17B10 (0.40) HSD17B10TDP1CYP3A4MAPTPDE4A
SCHEMBL20274462 0.86 TDP1 (0.35) HSD17B10TDP1CYP3A4MAPTPDE4A
SCHEMBL14435586 0.84 TDP1 (0.33) TDP1CYP3A4MAPTPDE4APDE4B
SCHEMBL182607 0.83 HSD17B10 (0.40) HSD17B10TDP1MEN1KMT2ACYP1A2
SCHEMBL3763099 0.80 HSD17B10 (0.41) HSD17B10TDP1CYP3A4MAPTMEN1
SCHEMBL6757630 0.78 HSD17B10 (0.38) HSD17B10TDP1
SCHEMBL27341083 0.78 PTPN1 (0.40) HSD17B10TDP1MEN1KMT2ACYP1A2
SCHEMBL28796108 0.78 HSD17B10 (0.38) HSD17B10TDP1
SCHEMBL27403870 0.78 MGAM (0.35) HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
CN-109554181-A Liquid crystal media and liquid crystal display comprising it 默克专利股份有限公司 2019-04-02 CN disclosed
CN-109207161-A Liquid crystal media and liquid crystal display comprising it 默克专利股份有限公司 2019-01-15 CN disclosed
CN-106045953-A Fluorinated dibenzofuran and dibenzothiophene derivative 默克专利股份有限公司 2016-10-26 CN disclosed
US-8435800-B2 Activated labeling reagents and methods for preparing and using the same BIOSIGHT LTD. (IL) 2013-05-07 US disclosed
US-20090203879-A1 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME BIOSIGHT LTD 2009-08-13 US disclosed
EP-1814908-A4 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME BIOSIGHT LTD (IL) 2009-07-01 EP disclosed
EP-1814908-A1 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME Biosight Ltd. (IL) 2007-08-08 EP disclosed
US-20070173592-A1 Perfluorostyrene compound, and coating solution and optical waveguide device using the same CHEMOPTICS INC. (KR) 2007-07-26 US disclosed
US-7202324-B2 Perfluorostyrene compound, and coating solution and optical waveguide device using the same CHEMOPTICS INC. (KR) 2007-04-10 US disclosed
WO-2006054310-A1 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME BIOSIGHT LTD. (IL) 2006-05-26 WO disclosed