Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528699 | 1.00 | HTR6 (0.83) | HTR6DRD2 | |
| SCHEMBL6533247 | 1.00 | HTR6 (0.83) | HTR6DRD2 | |
| SCHEMBL7482774 | 0.93 | HTR6 (0.71) | HTR6DRD2 | |
| SCHEMBL14469111 | 0.92 | HTR6 (0.82) | HTR6 | |
| SCHEMBL6529782 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5253765 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5253216 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL6530539 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5253195 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5253626 | 0.91 | HTR6 (1.00) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | claimed |
| CN-1918173-B | Novel indeno[2,1a]indenes and isoindol[2,1-a]indoles | SUVEN LIFE SCIENCES LTD | 2011-09-14 | — | — | CN | disclosed |
| EP-1704154-B1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2009-05-06 | — | — | EP | disclosed |
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | disclosed |
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-03-08 | — | — | US | disclosed |
| CN-1918173-A | Novel indeno[2,1a]indenes and isoindol[2,1-a]indoles | SUVEN LIFE SCIENCES (IN) | 2007-02-21 | — | — | CN | disclosed |
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | IDO1, IDO2, OPRD1 | HTR6 166/4885DRD2 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.