Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
| ▸ | OTUB1 | Q96FW1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058810 | 1.00 | HTR6 (0.41) | HTR6PARP1KDM4EATMUSP2 | |
| SCHEMBL14177903 | 1.00 | HTR6 (0.41) | HTR6PARP1KDM4EATMUSP2 | |
| SCHEMBL3324374 | 0.88 | HTR6 (0.53) | HTR6KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4058308 | 0.88 | HTR6 (0.53) | HTR6KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4049451 | 0.88 | HTR6 (0.53) | HTR6KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4054154 | 0.86 | HTR6 (0.44) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL14177900 | 0.86 | HTR6 (0.44) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL4058499 | 0.86 | HTR6 (0.42) | HTR6KDM4EATMCYP1A2CYP2C9 | |
| SCHEMBL4048282 | 0.86 | HTR6 (0.44) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL14177905 | 0.86 | HTR6 (0.42) | HTR6KDM4EATMCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1704154-B1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2009-05-06 | — | — | EP | claimed |
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | claimed |
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-03-08 | — | — | US | claimed |
| EP-1704154-A1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | Suven Life Sciences Limited (IN) | 2006-09-27 | — | — | EP | claimed |
| WO-2005066184-A1 | NOVEL INDENO[2,1A]INDENES AND ISOINDOL[2,1-A]INDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2005-07-21 | — | — | WO | claimed |
| EP-1704154-B1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2009-05-06 | — | — | EP | disclosed |
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | disclosed |
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-03-08 | — | — | US | disclosed |
| EP-1704154-A1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | Suven Life Sciences Limited (IN) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005066184-A1 | NOVEL INDENO[2,1A]INDENES AND ISOINDOL[2,1-A]INDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | IDO1, IDO2, OPRD1 | HTR6 166/4885PARP1 946/4885KDM4E 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.