Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941665 | 1.00 | CTSK (0.44) | CTSKLARS1DPP4DPP8DPP9 | |
| SCHEMBL4045680 | 0.91 | DPP4 (0.41) | CTSKLARS1DPP4DPP8DPP9 | |
| SCHEMBL4039220 | 0.88 | HSD17B10 (0.42) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL4041763 | 0.86 | CTSK (0.45) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL4044728 | 0.81 | DPP4 (0.40) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL4048380 | 0.81 | CTSK (0.64) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL5941514 | 0.81 | CTSK (0.64) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL4039127 | 0.81 | CTSK (0.61) | CTSK | |
| SCHEMBL4049054 | 0.79 | DPP4 (0.52) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL13909140 | 0.79 | CTSK (0.61) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |