Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049237 | 0.91 | CTSK (0.44) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL5941665 | 0.91 | CTSK (0.44) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL4039220 | 0.89 | HSD17B10 (0.42) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL4041763 | 0.85 | CTSK (0.45) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL4044700 | 0.82 | CTSK (0.52) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL4039382 | 0.82 | CTSK (0.53) | DPP8DPP9CTSK | |
| SCHEMBL4038231 | 0.81 | SMYD3 (0.39) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL4044728 | 0.80 | DPP4 (0.40) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL4045856 | 0.80 | CTSK (0.65) | DPP8DPP9CTSKTP53HSD11B1 | |
| SCHEMBL4045677 | 0.80 | HSD11B1 (0.34) | TP53HSD11B1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |