Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055565 | 0.85 | PIK3CA (0.57) | TTKPIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL13905159 | 0.83 | PIK3CG (0.53) | TTKPIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL44694 | 0.81 | ALDH1A3 (0.50) | ADORA2AMAPK1ALDH1A3CTSSCTSK | |
| SCHEMBL13905321 | 0.81 | PIK3CA (0.50) | ABL1PIK3CA | |
| SCHEMBL12664426 | 0.77 | CSNK1D (0.55) | ADORA2ACSNK1DCSNK1EPIK3CAALDH1A3 | |
| SCHEMBL24509581 | 0.76 | ADORA2A (0.48) | ADORA2ACSNK1DCSNK1EALDH1A3NPC1 | |
| SCHEMBL30558747 | 0.76 | ADORA2A (0.48) | ADORA2ACSNK1DCSNK1EALDH1A3NPC1 | |
| SCHEMBL4340895 | 0.74 | PIK3CA (0.75) | ABL1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL44397 | 0.73 | ALDH1A3 (0.53) | ADORA2AALDH1A3CTSSCTSKNPC1 | |
| SCHEMBL13905328 | 0.72 | PIK3CA (0.37) | TTKPIK3CAMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027733-A1 | (2-PYRIDIN-3-YLIMIDAZO[1,2-B]PYRIDAZIN-6-YL) UREA DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009027733-A1 | (2-PYRIDIN-3-YLIMIDAZO[1,2-B]PYRIDAZIN-6-YL) UREA DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | WO | disclosed |