Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888039 | 0.88 | IDO1 (0.64) | IDO1AGXTKDM4EL3MBTL1MAOB | |
| SCHEMBL6671514 | 0.88 | TSHR (0.52) | IDO1KDM4ETSHR | |
| Hydroxyamine SCHEMBL8923579 | 0.86 | IDO1 (0.62) | IDO1AGXTKDM4EL3MBTL1MAOB | |
| SCHEMBL15233235 | 0.85 | — | — | |
| SCHEMBL23462 | 0.85 | — | — | |
| Methane SCHEMBL27485154 | 0.83 | PTGS1 (0.53) | IDO1AGXTPTGS1MEN1KMT2A | |
| SCHEMBL22304854 | 0.81 | IDO1 (0.56) | IDO1AGXTKDM4EL3MBTL1MAOB | |
| SCHEMBL713596 | 0.81 | MAOB (0.67) | MEN1KMT2AMAOBAPPNR4A2 | |
| Ethylene SCHEMBL27825958 | 0.80 | PTGS1 (0.52) | IDO1AGXTPTGS1MEN1KMT2A | |
| Hydroxyamine SCHEMBL8923569 | 0.80 | LOXL2 (0.55) | IDO1AGXTPTGS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |