Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 5/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23462 | 0.94 | — | — | |
| SCHEMBL15233235 | 0.94 | — | — | |
| Methane SCHEMBL27485154 | 0.92 | PTGS1 (0.53) | LOXL2PTGS1TAAR1IDO1AGXT | |
| Ethylene SCHEMBL27825958 | 0.89 | PTGS1 (0.52) | LOXL2PTGS1TAAR1IDO1AGXT | |
| SCHEMBL4412749 | 0.86 | PTGS1 (0.60) | LOXL2PTGS1TAAR1IDO1AGXT | |
| SCHEMBL15437070 | 0.86 | TAAR1 (0.54) | LOXL2PTGS1TAAR1IDO1TSHR | |
| SCHEMBL13056318 | 0.82 | PTGS1 (0.43) | LOXL2PTGS1TAAR1IDO1AGXT | |
| SCHEMBL6161106 | 0.80 | LTA4H (0.65) | LOXL2PTGS1IDO1AGXTMEN1 | |
| SCHEMBL12973307 | 0.80 | NFE2L2 (0.54) | PTGS1 | |
| SCHEMBL5473183 | 0.80 | KMT2A (0.51) | LOXL2PTGS1IDO1TRPA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625067-A | Cyclopentane ether derivatives, processes for their production, and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| EP-0558570-B1 | CYCLOPENTANE ETHER DERIVATIVES, METHODS FOR PREPARING THEM AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0558570-A1 | CYCLOPENTANE ETHER DERIVATIVES, METHODS FOR PREPARING THEM AND THEIR USE IN PHARMACEUTICALS. | SCHERING AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009573-A2 | CYCLOPENTANE ETHER DERIVATIVES, METHODS FOR PREPARING THEM AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1992-06-11 | — | — | WO | disclosed |