Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051379 | 0.97 | CNR1 (0.43) | CNR1CNR2F10HTR3AJAK2 | |
| SCHEMBL4049686 | 0.91 | CNR1 (0.45) | CNR1CNR2F10HTR3A | |
| SCHEMBL4053731 | 0.90 | CNR1 (0.44) | CNR1CNR2F10HTR3AKDM4C | |
| SCHEMBL13690941 | 0.90 | CNR1 (0.47) | CNR1CNR2F10HTR3A | |
| SCHEMBL4057565 | 0.88 | CNR1 (0.43) | CNR1CNR2HTR3A | |
| SCHEMBL4051609 | 0.87 | CNR1 (0.48) | CNR1CNR2KDM4C | |
| SCHEMBL13690956 | 0.87 | CNR1 (0.48) | CNR1CNR2KDM4C | |
| SCHEMBL13690948 | 0.87 | HTR3A (0.47) | CNR1CNR2F10HTR3A | |
| SCHEMBL4056091 | 0.86 | CNR1 (0.59) | CNR1CNR2 | |
| SCHEMBL4049934 | 0.86 | CNR1 (0.45) | CNR1CNR2JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |