Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | CFD | P00746 | 3/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690985 | 1.00 | CNR1 (0.51) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL13691004 | 0.92 | CNR1 (0.47) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL4049851 | 0.92 | CNR1 (0.47) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL13691063 | 0.92 | CNR1 (0.49) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL4051582 | 0.92 | CNR1 (0.42) | CNR1CNR2CFDHTR4HTR3A | |
| SCHEMBL4050200 | 0.91 | CNR1 (0.43) | CNR1CNR2CFDHTR2CSLC6A4 | |
| SCHEMBL4057752 | 0.91 | CNR1 (0.57) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL4051299 | 0.90 | CNR1 (0.47) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL13690828 | 0.90 | CNR1 (0.47) | CNR1CNR2ADORA2AADORA1PTGER4 | |
| SCHEMBL4049667 | 0.89 | CNR1 (0.41) | CNR1CNR2SSTR4CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |