Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.51 |
| ▸ | CTSL | P07711 | 8/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045942 | 0.92 | CTSK (0.41) | CTSKCTSLCTSS | |
| SCHEMBL4042251 | 0.89 | CTSK (0.50) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4046471 | 0.88 | CTSK (0.47) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4045960 | 0.88 | CTSK (0.41) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4045748 | 0.87 | CTSK (0.51) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4046026 | 0.87 | CTSK (0.51) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4046025 | 0.87 | CTSK (0.49) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4045333 | 0.87 | CTSK (0.53) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4046943 | 0.85 | CTSK (0.50) | CTSKCTSLCTSSKDM4EALDH1A1 | |
| SCHEMBL4045548 | 0.85 | CTSK (0.51) | CTSKCTSLCTSSKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |