Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050710 | 1.00 | ALOX5 (0.41) | ALOX5PTPN1HPGDHTTCISD1 | |
| SCHEMBL4059813 | 1.00 | ALOX5 (0.41) | ALOX5PTPN1HPGDHTTCISD1 | |
| SCHEMBL4059814 | 1.00 | ALOX5 (0.41) | ALOX5PTPN1HPGDHTTCISD1 | |
| SCHEMBL4053974 | 0.93 | PTPN1 (0.39) | ALOX5PTPN1HPGDPOLBMAOA | |
| SCHEMBL4055053 | 0.93 | PTPN1 (0.39) | ALOX5PTPN1HPGDCISD1POLB | |
| SCHEMBL4053976 | 0.93 | PTPN1 (0.39) | ALOX5PTPN1HPGDPOLBMAOA | |
| SCHEMBL4051990 | 0.92 | PTPN1 (0.39) | ALOX5PTPN1HPGDPOLBMAOA | |
| SCHEMBL4053526 | 0.92 | PTPN1 (0.39) | ALOX5PTPN1HPGDPOLBMAOA | |
| SCHEMBL4048862 | 0.92 | MEN1 (0.41) | ALOX5PTPN1HPGDCISD1POLB | |
| SCHEMBL4057137 | 0.92 | PTPN1 (0.40) | ALOX5PTPN1HPGDCISD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |