Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | MAX | P61244 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048856 | 1.00 | MEN1 (0.41) | MEN1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4057139 | 0.93 | PTPN1 (0.40) | MEN1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4057137 | 0.93 | PTPN1 (0.40) | MEN1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4050710 | 0.92 | ALOX5 (0.41) | PTPN1ALOX5HPGDPOLBMAOA | |
| SCHEMBL4059814 | 0.92 | ALOX5 (0.41) | PTPN1ALOX5HPGDPOLBMAOA | |
| SCHEMBL4050707 | 0.92 | ALOX5 (0.41) | PTPN1ALOX5HPGDPOLBMAOA | |
| SCHEMBL4059813 | 0.92 | ALOX5 (0.41) | PTPN1ALOX5HPGDPOLBMAOA | |
| SCHEMBL4054941 | 0.91 | HPGD (0.48) | MEN1MAPTKMT2APTPN1ALOX5 | |
| SCHEMBL4054943 | 0.91 | HPGD (0.48) | MEN1MAPTKMT2APTPN1ALOX5 | |
| SCHEMBL4050515 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |