Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 3/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5942111 | 1.00 | CTSK (0.51) | CTSKPIK3CDPREPFAPGAA | |
| SCHEMBL4044700 | 0.88 | CTSK (0.52) | CTSKPIK3CDPREPFAPDPP4 | |
| SCHEMBL5941514 | 0.88 | CTSK (0.64) | CTSKPIK3CDFAPDPP4DPP8 | |
| SCHEMBL4048380 | 0.88 | CTSK (0.64) | CTSKPIK3CDFAPDPP4DPP8 | |
| SCHEMBL4047662 | 0.85 | CTSK (0.41) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL4043042 | 0.83 | CTSK (0.68) | CTSKPIK3CDPREPFAPCTSS | |
| SCHEMBL4040770 | 0.82 | CTSK (0.48) | CTSKDPP4DPP8DPP9DPP7 | |
| SCHEMBL4039220 | 0.81 | HSD17B10 (0.42) | CTSKGAADPP4DPP8DPP9 | |
| SCHEMBL4049054 | 0.81 | DPP4 (0.52) | CTSKFAPDPP4DPP8DPP9 | |
| SCHEMBL4044250 | 0.80 | CTSK (0.49) | CTSKDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |