Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.71 |
| ▸ | MMP3 | P08254 | 1/20 | 0.71 |
| ▸ | CTSD | P07339 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050829 | 1.00 | MMP13 (0.71) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL4049602 | 0.99 | MMP13 (0.69) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL4049607 | 0.99 | MMP13 (0.69) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL4057275 | 0.89 | HRH3 (0.58) | MMP13MMP3HPGDPOLBPTGS2 | |
| SCHEMBL4060000 | 0.87 | MMP3 (0.71) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL4060003 | 0.87 | MMP3 (0.71) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL1250159 | 0.83 | PTPN1 (0.82) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL4056380 | 0.83 | HPGD (0.82) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL1250155 | 0.83 | PTPN1 (0.82) | MMP13MMP3CTSDHPGDPTPN1 | |
| SCHEMBL4050762 | 0.83 | HPGD (0.82) | MMP13MMP3CTSDHPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |