Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055789 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL8288443 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL25739943 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL26789169 | 0.82 | USP2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL26789172 | 0.82 | USP2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL8288440 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL3154658 | 0.82 | USP2 (0.70) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL24575950 | 0.81 | HPGD (0.72) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL5674448 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| Hydrochloric Acid SCHEMBL4218039 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2USP2HPGDTP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472166-B2 | Inhibition of mycobacterial type VII secretion | STICHTING VUMC (NL) | 2025-11-18 | — | — | US | disclosed |
| EP-4021898-B1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | Stichting Amsterdam UMC (NL) | 2024-05-29 | — | — | EP | disclosed |
| US-20220280487-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | STICHTING VU (NL) | 2022-09-08 | — | — | US | disclosed |
| EP-4021898-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | Stichting VUmc (NL) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021040519-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | STICHTING VUMC (NL) | 2021-03-04 | — | — | WO | disclosed |
| WO-2021040519-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | STICHTING VUMC (NL) | 2021-03-04 | — | — | WO | disclosed |
| EP-1819710-B1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | ALMIRALL LAB (ES) | 2009-03-11 | — | — | EP | disclosed |
| US-20090029955-A1 | Pyridothienopyrimidine Derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2009-01-29 | — | — | US | disclosed |
| EP-1819710-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058724-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-08 | — | — | WO | disclosed |
| EP-0010231-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING N-SUBSTITUTED AMIDO AND IMIDO SUBSTITUENTS AND PROCESS FOR THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4218557-A | PROTECTIVE COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029955-A1 | Pyridothienopyrimidine Derivatives | PNPO, PDE4A, DPYD | SMN1; SMN2 760/4885USP2 2894/4885HPGD 35/4885 |
| US-12472166-B2 | Inhibition of mycobacterial type VII secretion | CFTR, ABCB11, ABCC2 | SMN1; SMN2 3835/4885USP2 890/4885HPGD 2319/4885 |
| US-20220280487-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | CFTR, ABCB11, ABCC2 | SMN1; SMN2 3835/4885USP2 890/4885HPGD 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.