Azelaic Acid

Azelaic Acid

SCHEMBL4051535

C=CC=C.O=C(O)CCCCCCCC(=O)O

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
LMNA P02545 3/20 0.71
NFKB1 P19838 1/20 0.71
PMP22 Q01453 1/20 0.71
ABCC4 O15439 1/20 0.68
MAPT P10636 1/20 0.68
GPR84 Q9NQS5 8/20 0.57
FFAR1 O14842 2/20 0.57
FFAR4 Q5NUL3 2/20 0.57
SLC22A6 Q4U2R8 2/20 0.56
PPARG P37231 6/20 0.55
PPARD Q03181 6/20 0.55
PPARA Q07869 6/20 0.55
HDAC11 Q96DB2 5/20 0.55
ALDH1A1 P00352 3/20 0.55
TLR2 O60603 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MEN1 O00255 2/20 0.55
FABP4 P15090 2/20 0.55
ALOX15 P16050 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL4053732 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22ABCC4
Butadiene SCHEMBL2257807 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22ABCC4
Octanedioate SCHEMBL4052467 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22ABCC4
Adipic Acid SCHEMBL851390 0.97 LMNA (0.69) TSHRLMNANFKB1PMP22ABCC4
Glutarate SCHEMBL4061457 0.91 SLC22A6 (0.69) TSHRLMNANFKB1PMP22ABCC4
Dodecanoate SCHEMBL4238219 0.88 GPR84 (0.77) TSHRLMNAMAPTGPR84FFAR1
Sebacic Acid SCHEMBL7057259 0.86 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4
Sebacic Acid SCHEMBL1046750 0.86 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4
Sebacic Acid SCHEMBL7053358 0.86 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4
Azelaic Acid SCHEMBL4945040 0.86 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103539885-B A kind of preparation method of the Thermo-sensitive sugar-containing polymer with biologic specificity identification DONGHUA UNIVERSITY (CN) 2016-05-04 CN claimed
CN-105155139-A Preparation method for electrostatic spinning glucose ester/acrylonitrile copolymer nanofiber membrane and application thereof LANGSHA KNITTING CO LTD 2015-12-16 CN claimed
CN-103614860-A Method for preparing glucose azelaic acid divinyl ester/N-isopropylacrylamide copolymer nanofiber membrane UNIV DONGHUA 2014-03-05 CN claimed
CN-103539885-B A kind of preparation method of the Thermo-sensitive sugar-containing polymer with biologic specificity identification DONGHUA UNIVERSITY (CN) 2016-05-04 CN disclosed
CN-105155139-A Preparation method for electrostatic spinning glucose ester/acrylonitrile copolymer nanofiber membrane and application thereof LANGSHA KNITTING CO LTD 2015-12-16 CN disclosed
CN-103614860-A Method for preparing glucose azelaic acid divinyl ester/N-isopropylacrylamide copolymer nanofiber membrane UNIV DONGHUA 2014-03-05 CN disclosed
US-7507516-B2 Toner and method of manufacturing toner KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-03-24 US disclosed
US-20060292481-A1 Toner and method of manufacturing toner KONICA MINOLTA BUSINES TECHNOLOGIES, INC. 2006-12-28 US disclosed