Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL425185 | 0.98 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL80718 | 0.98 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL7263491 | 0.98 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Bromide SCHEMBL3641371 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Iodide SCHEMBL16961611 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL9653571 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Ammonia Solution, Strong SCHEMBL10810468 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL7263493 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Bromide SCHEMBL28903217 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Benzene SCHEMBL27897171 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7620439-B2 | Comprising pressure sensitive adhesive, electrolyte comprising water soluble or water dispersible organic chloride, and humectant, wherein electrolyte and humectant are at least partially miscible in one another; for biomedical articles such as biomedical electrodes | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-11-17 | — | — | US | claimed |
| JP-2009503235-A | — | — | 2009-01-29 | — | — | JP | claimed |
| EP-1917318-A1 | CONDUCTIVE ADHESIVES AND BIOMEDICAL ARTICLES INCLUDING SAME | 3M Innovative Properties Company (US) | 2008-05-07 | — | — | EP | claimed |
| WO-2007019115-A1 | CONDUCTIVE ADHESIVES AND BIOMEDICAL ARTICLES INCLUDING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-02-15 | — | — | WO | claimed |
| US-20070032719-A1 | Conductive adhesives and biomedical articles including same | 3M INNOVATIVE PROPERTIES COMPANY | 2007-02-08 | — | — | US | claimed |