Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002050 | 0.88 | POLB (0.44) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4051643 | 0.87 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL7992120 | 0.87 | ADORA2A (0.56) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4050785 | 0.87 | EPHX1 (0.61) | KMT2AMEN1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4049840 | 0.83 | HDAC3 (0.47) | SMN1; SMN2HPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL2631520 | 0.79 | HPGD (0.50) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL23440313 | 0.78 | HPGD (0.71) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL18397598 | 0.78 | HPGD (0.71) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL19070281 | 0.78 | HPGD (0.48) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL29699833 | 0.78 | HPGD (0.71) | KMT2AMEN1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |