Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 4/20 | 0.44 |
| ▸ | BCR | P11274 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052776 | 0.89 | ABL1 (0.50) | HDAC3HDAC1HDAC2ABL1BCR | |
| SCHEMBL4051880 | 0.83 | KMT2A (0.52) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8002050 | 0.80 | POLB (0.44) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13626256 | 0.79 | HTR1A (0.60) | HDAC3HDAC1HDAC2RHOAABL1 | |
| SCHEMBL4452303 | 0.79 | HTR1A (0.60) | HDAC3HDAC1HDAC2RHOAABL1 | |
| SCHEMBL7992120 | 0.79 | ADORA2A (0.56) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4049846 | 0.74 | HDAC2 (0.46) | HDAC3HDAC1HDAC2RHOAABL1 | |
| SCHEMBL4051643 | 0.73 | KMT2A (0.60) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4326042 | 0.71 | HDAC3 (0.43) | HDAC3HDAC1HDAC2RHOAABL1 | |
| SCHEMBL4050785 | 0.71 | EPHX1 (0.61) | NPC1TP53HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |