Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051880 | 0.87 | KMT2A (0.52) | ADORA2AADORA1EPHX1KMT2AMEN1 | |
| SCHEMBL8002050 | 0.84 | POLB (0.44) | ADORA2AADORA1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4049840 | 0.79 | HDAC3 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4050785 | 0.75 | EPHX1 (0.61) | ADORA2AADORA1EPHX1KMT2AMEN1 | |
| SCHEMBL4051643 | 0.75 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL7383605 | 0.73 | TSHR (0.59) | ADORA2AADORA1EPHX1KMT2AMEN1 | |
| SCHEMBL28863714 | 0.72 | GAA (0.68) | ADORA2AADORA1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23850471 | 0.71 | TSHR (0.53) | ADORA2AADORA1EPHX1KMT2AMEN1 | |
| SCHEMBL11480252 | 0.70 | ALDH1A1 (0.81) | ADORA2AADORA1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6882525 | 0.70 | ALDH1A1 (0.81) | ADORA2AADORA1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |