Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | RXRB | P28702 | 2/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874405 | 0.84 | MAOB (0.69) | RAB9APARP10MAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL22386732 | 0.84 | SMN1; SMN2 (0.69) | RXRARXRBADAMTS4MMP2MMP13 | |
| SCHEMBL18259995 | 0.82 | NR4A2 (0.68) | RXRARXRBRAB9ANPC1PARP10 | |
| SCHEMBL6816962 | 0.82 | MAOB (0.69) | RXRARXRBPARP10MAOBSMN1; SMN2 | |
| SCHEMBL2558683 | 0.82 | NR4A2 (0.68) | RXRARXRBRAB9ANPC1PARP10 | |
| SCHEMBL22741541 | 0.82 | PARP10 (0.62) | RAB9APARP10SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL18946710 | 0.81 | RAB9A (0.68) | RXRARXRBRAB9ANPC1PARP10 | |
| SCHEMBL18259961 | 0.81 | NPC1 (0.73) | RXRARXRBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10464779 | 0.81 | NPC1 (0.73) | RXRARXRBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23223734 | 0.81 | RAB9A (0.69) | RAB9ANPC1PARP10MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |