Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | PTPRC | P08575 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357464 | 0.65 | IDO1 (0.52) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL1650480 | 0.65 | IDO1 (1.00) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL11758095 | 0.64 | PTPRC (0.34) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL24404193 | 0.60 | IDO1 (0.52) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL15762826 | 0.60 | IDO1 (0.52) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL6545149 | 0.60 | — | — | |
| 1,2-Naphthoquinone SCHEMBL173316 | 0.59 | PTPRC (1.00) | IDO1PTPRCCES1KDM4EMEN1 | |
| 1,2-Naphthoquinone SCHEMBL15167712 | 0.59 | PTPRC (1.00) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL16900338 | 0.58 | PTPRC (0.53) | IDO1PTPRCCES1KDM4EMEN1 | |
| SCHEMBL2527823 | 0.58 | PTPRC (0.52) | IDO1PTPRCCES1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330941-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-2076518-A1 | TRICYCLIC SPIRO-OXINDOLE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008046046-A1 | TRICYCLIC SPIRO-OXINDOLE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-04-17 | — | — | WO | disclosed |