Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 1.00 |
| ▸ | CDC25B | P30305 | 4/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | S100A4 | P26447 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407655 | 0.70 | IDO1 (0.54) | IDO1CDC25BMAP2K1PIN1MAOA | |
| SCHEMBL24404193 | 0.69 | IDO1 (0.52) | IDO1CDC25BMAP2K1MAOAMAPT | |
| SCHEMBL15762826 | 0.69 | IDO1 (0.52) | IDO1CDC25BMAP2K1MAOAMAPT | |
| SCHEMBL31357464 | 0.69 | IDO1 (0.52) | IDO1CDC25BMAP2K1PIN1MAOA | |
| SCHEMBL4052052 | 0.65 | IDO1 (0.48) | IDO1MAPTCRBNKMT2AKDM4E | |
| SCHEMBL6364569 | 0.62 | DNMT1 (0.49) | IDO1MAP2K1MAPTKMT2AS100A4 | |
| SCHEMBL21305078 | 0.62 | MAP2K1 (0.61) | IDO1MAP2K1MAOAMAOBMAPT | |
| SCHEMBL311991 | 0.62 | ALOX15 (0.48) | IDO1MAP2K1MAPTCRBNALDH1A1 | |
| Naphthoquinone SCHEMBL28536412 | 0.62 | IDO1 (0.70) | IDO1CDC25BMAP2K1PIN1MAOA | |
| SCHEMBL3958516 | 0.62 | IDO1 (0.44) | IDO1CDC25BMAP2K1PIN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | claimed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | claimed |
| EP-0957891-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-03-19 | — | — | EP | claimed |
| US-6037326-A | APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE | GILLETTE COMPANY, THE | 2000-03-14 | — | — | US | claimed |
| EP-0957891-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1998029086-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1998-07-09 | — | — | WO | claimed |
| EP-0324109-B1 | 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1993-09-29 | — | — | EP | claimed |
| US-4791130-A | ANTITUMOR AGENTS. | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-12-13 | — | — | US | claimed |
| US-11530181-B2 | IL-6 inhibitors and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-12-20 | — | — | US | disclosed |
| CN-110734423-B | Indoloquinone indoleamine-2,3-dioxygenase inhibitor and medicinal application thereof | 复旦大学 | 2022-07-08 | — | — | CN | disclosed |
| US-20210206718-A1 | IL-6 INHIBITORS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2021-07-08 | — | — | US | disclosed |
| WO-2019165158-A1 | IL-6 INHIBITORS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-08-29 | — | — | WO | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| EP-0957891-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6037326-A | APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE | GILLETTE COMPANY, THE | 2000-03-14 | — | — | US | disclosed |
| EP-0957891-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998029086-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1998-07-09 | — | — | WO | disclosed |
| EP-0242160-A2 | Mitomycin derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1987-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530181-B2 | IL-6 inhibitors and methods of treatment | IL6, IL6ST, IL2 | IDO1 297/4885CDC25B 2296/4885MAP2K1 2227/4885 |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | KRT18, NDUFA1, NDUFA2 | IDO1 1036/4885CDC25B 1366/4885MAP2K1 205/4885 |
| US-20210206718-A1 | IL-6 INHIBITORS AND METHODS OF TREATMENT | IL6, IL6ST, IL2 | IDO1 297/4885CDC25B 2296/4885MAP2K1 2227/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | IDO1 3218/4885CDC25B 1550/4885MAP2K1 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.