Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012374 | 0.87 | MAOB (0.54) | MAOAMAOBALDH1A1LMNAMAPT | |
| SCHEMBL4049966 | 0.86 | SMN1; SMN2 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1164139 | 0.83 | MAOB (0.74) | MAOAMAOBALDH1A1RAB9ANPC1 | |
| SCHEMBL1443663 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6687219 | 0.82 | MAOB (0.66) | MAOAMAOBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1164373 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1864244 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1239921 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL10497693 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1164661 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |