Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850828 | 0.79 | CCNC (0.37) | CCNCCDK8AXLTP53CYP3A4 | |
| SCHEMBL4048670 | 0.79 | SIRT3 (0.34) | TP53CYP3A4MAPTTSHRMAPK1 | |
| SCHEMBL20551380 | 0.79 | GAA (0.39) | CYP3A4 | |
| SCHEMBL4662739 | 0.79 | LOXL2 (0.36) | — | |
| SCHEMBL6118889 | 0.78 | RPS6KA3 (0.36) | — | |
| Bromide SCHEMBL4936805 | 0.78 | LOXL2 (0.35) | — | |
| SCHEMBL16011547 | 0.77 | AXL (0.36) | CCNCCDK8AXLTP53CYP3A4 | |
| SCHEMBL7358831 | 0.76 | CDC25B (0.36) | — | |
| SCHEMBL3819175 | 0.76 | SIRT3 (0.38) | TP53CYP3A4MAPTTSHRMAPK1 | |
| Bromide SCHEMBL6450377 | 0.74 | SIRT3 (0.37) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009114552-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-09-17 | — | — | WO | disclosed |