Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4936805 | 0.98 | LOXL2 (0.35) | LOXL2RPS6KA3 | |
| SCHEMBL4052201 | 0.79 | CCNC (0.38) | — | |
| SCHEMBL20551380 | 0.78 | GAA (0.39) | — | |
| SCHEMBL4048670 | 0.78 | SIRT3 (0.34) | — | |
| SCHEMBL27738537 | 0.77 | LOXL2 (0.37) | LOXL2RPS6KA3 | |
| SCHEMBL6118889 | 0.76 | RPS6KA3 (0.36) | RPS6KA3 | |
| SCHEMBL7358831 | 0.74 | CDC25B (0.36) | — | |
| SCHEMBL3819175 | 0.74 | SIRT3 (0.38) | — | |
| Bromide SCHEMBL6450377 | 0.73 | SIRT3 (0.37) | — | |
| SCHEMBL15057387 | 0.73 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004623-A1 | PYRIDYL- AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007110344-A1 | PYRIDYL- AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-10-04 | — | — | WO | disclosed |