⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779815 | 0.79 | — | — | |
| SCHEMBL1634157 | 0.69 | — | — | |
| SCHEMBL11235276 | 0.69 | — | — | |
| SCHEMBL2856716 | 0.67 | — | — | |
| SCHEMBL2856718 | 0.67 | — | — | |
| SCHEMBL1960558 | 0.67 | — | — | |
| SCHEMBL11689457 | 0.67 | — | — | |
| SCHEMBL3082161 | 0.66 | — | — | |
| SCHEMBL10717619 | 0.64 | — | — | |
| SCHEMBL11409206 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377953-B2 | Isothiazole and pyrazole derivatives as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377953-B2 | Isothiazole and pyrazole derivatives as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-20110301034-A1 | ISOTHIAZOLE AND PYRAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301034-A1 | ISOTHIAZOLE AND PYRAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110224241-A1 | ISOTHIAZOLE AND PYRAZOLE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224241-A1 | ISOTHIAZOLE AND PYRAZOLE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010069877-A1 | ISOTHIAZOLE AND PYRAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
| EP-1503998-B1 | HETEROARYL SUBSTITUTED SPIROCYCLIC SUFAMIDES FOR INHIBITION OF GAMMA SECRETASE | MERCK SHARP & DOHME (GB) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009007098-A1 | ISOTHIAZOLE AND PYRAZOLE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-15 | — | — | WO | disclosed |
| US-20080070895-A1 | Heteroaryl substituted spirocyclic sulfamides for inhibition of gamma secretase | COLLINS IAN J | 2008-03-20 | — | — | US | disclosed |
| WO-1999045201-A1 | METHOD FOR IMPROVED WET STRENGTH PAPER | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| EP-0076410-B1 | REACTIVE ANTHRAQUINONE DYES | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4528408-A | Trans-3-substituted-1-indanol and insecticidal ester derivatives | FMC CORPORATION (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0028351-B1 | REACTIVE DYESTUFFS AND THEIR USE IN DYEING MATERIALS CONTAINING OH OR NH | BAYER AG (DE) | 1984-02-22 | — | — | EP | disclosed |
| EP-0076410-A2 | Reactive anthraquinone dyes | BAYER AG (DE) | 1983-04-13 | — | — | EP | disclosed |
| US-4362744-A | Trans-3-substituted-1-indanol insecticidal ester derivatives | FMC CORPORATION (US) | 1982-12-07 | — | — | US | disclosed |
| EP-0028351-A2 | Reactive dyestuffs and their use in dyeing materials containing OH or NH | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4017477-A | 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |