Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347531 | 1.00 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1HPGDBRD4 | |
| SCHEMBL38471077 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL10391045 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL8471483 | 0.87 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1HPGDBRD4 | |
| SCHEMBL7717844 | 0.84 | CYP1A2 (0.59) | CYP1A2MAPTPOLBCNR2CNR1 | |
| SCHEMBL7829452 | 0.83 | CYP1A2 (0.56) | CYP1A2ALDH1A1TSHRKMT2AMCL1 | |
| SCHEMBL669648 | 0.83 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL10884829 | 0.81 | UGT2B7 (0.42) | CYP1A2TSHRMEN1KMT2AMCL1 | |
| SCHEMBL6914442 | 0.81 | CYP1A2 (0.54) | CYP1A2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL3914643 | 0.81 | ATM (0.60) | CYP1A2KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384028-B | Synthesis method of 4-acetyl-1-naphthoic acid | 济南久隆医药科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-117384028-A | Synthesis method of 4-acetyl-1-naphthoic acid | 济南久隆医药科技有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-114113388-B | Method for detecting related substances in 4-oxime methyl-1-naphthoic acid | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114113388-A | Method for detecting related substances in 4-oximinomethyl-1-naphthoic acid | 丽珠集团新北江制药股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-109761775-B | Method for purifying 4-acetyl-1-methylnaphthalene from acetyl methylnaphthalene mixture | 湖北海力环保科技股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| EP-0087269-B1 | PLANT GROWTH REGULATORS | COALITE GROUP PLC (GB) | 1986-11-20 | — | — | EP | claimed |
| CN-119638567-A | Refining method of 1, 4-naphthalene dicarboxylic acid | 江苏八巨药业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-117384028-B | Synthesis method of 4-acetyl-1-naphthoic acid | 济南久隆医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-117384028-B | Synthesis method of 4-acetyl-1-naphthoic acid | 济南久隆医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-11-28 | — | — | US | disclosed |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-05-07 | — | — | US | disclosed |
| CN-117384028-A | Synthesis method of 4-acetyl-1-naphthoic acid | 济南久隆医药科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117384028-A | Synthesis method of 4-acetyl-1-naphthoic acid | 济南久隆医药科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2009148290-A2 | 3-SUBSTITUTED PROPANAMINE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2009-12-10 | — | — | WO | disclosed |
| EP-0087269-B1 | PLANT GROWTH REGULATORS | COALITE GROUP PLC (GB) | 1986-11-20 | — | — | EP | disclosed |
| EP-0087269-A1 | Plant growth regulators | COALITE GROUP PLC (GB) | 1983-08-31 | — | — | EP | disclosed |
| US-4249022-A | Process for the manufacture of 1,4-disubstituted bicyclic or tricyclic compounds and new 1,4-disubstituted bicyclic compounds | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4154754-A | 1,4-Dicyanonaphthalenes | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4048212-A | Process for the manufacture of 1,4-dicyanonaphthalenes | CIBA-GEIGY CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4011261-A | PROCESS FOR THE MANUFACTURE OF 1,4-DISUBSTITUTED BICYCLIC OR TRICYCLIC COMPOUNDS AND NEW 1,4-DISUBSTITUTED BICYCLIC COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | GAP43, NLN, SMN1; SMN2 | CYP1A2 4648/4885KDM4E 3736/4885ALDH1A1 1731/4885 |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | CYP1A2 4648/4885KDM4E 3736/4885ALDH1A1 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.