SCHEMBL669648

SCHEMBL669648

Cc1ccc(C(=O)O)c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
SLC16A3 O15427 1/20 0.50
WDR5 P61964 1/20 0.48
ALDH1A1 P00352 5/20 0.48
ALOX15 P16050 1/20 0.48
MCL1 Q07820 1/20 0.48
MYC P01106 2/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 2/20 0.47
LDHA P00338 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
ALOX12 P18054 1/20 0.47
ATIC P31939 1/20 0.47
CDC25B P30305 1/20 0.46
CNR2 P34972 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29265048 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6916663 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6914124 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6916342 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6917187 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6914126 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6912829 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6916659 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6914442 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3
SCHEMBL6917139 0.98 CYP1A2 (0.54) CYP1A2NR4A1NR4A2NR4A3SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841727-A Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid 湖南第一师范学院 2025-04-18 CN claimed
CN-119638567-A Refining method of 1, 4-naphthalene dicarboxylic acid 江苏八巨药业有限公司 2025-03-18 CN claimed
CN-119591645-A Isoquinoline-5-formic acid coordinated catalyst, composite catalyst, preparation method and application 上海元革新材料科技有限公司 2025-03-11 CN claimed
CN-119490406-A Preparation method of 4-formylnaphthalene-1-carboxylic acid methyl ester 长沙创新药物工业技术研究院有限公司 2025-02-21 CN claimed
CN-118164841-A Preparation method of 1-methyl-4-naphthoic acid 黄石市利福达医药化工有限公司 2024-06-11 CN claimed
CN-118146085-A Treatment method for material ending in middle of reaction for preparing 1, 4-naphthalene dicarboxylic acid by oxidizing 1-methyl-4-naphthalene carboxylic acid by oxygen 黄石市利福达医药化工有限公司 2024-06-07 CN claimed
CN-118108762-A Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof 四川东材科技集团股份有限公司 2024-05-31 CN claimed
CN-117886695-A Synthesis method of aforana key intermediate 4-formyl-1-methyl naphthoate 浙江工业大学 2024-04-16 CN claimed
CN-117820107-A Preparation method of 1,4-naphthalene dicarboxylic acid 荣峰投资控股有限公司 2024-04-05 CN claimed
CN-117416983-A Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method 中国科学院青海盐湖研究所 2024-01-19 CN claimed
CN-114113388-A Method for detecting related substances in 4-oximinomethyl-1-naphthoic acid 丽珠集团新北江制药股份有限公司 2022-03-01 CN claimed
CN-113336640-A Method for reducing content of 1, 4-naphthalenedicarboxylic acid impurities 黄石市利福达医药化工有限公司 2021-09-03 CN claimed
CN-109836618-B Modification method of aluminum oxide 中国石油天然气股份有限公司 2021-03-30 CN claimed
CN-111440137-A 3, 4-benzocoumarin derivative and preparation method and application thereof 华东理工大学 2020-07-24 CN claimed
CN-111410603-A Benzanthrone derivative, preparation method thereof and application thereof in functional pigment 上海甘田光学材料有限公司 2020-07-14 CN claimed
CN-109836618-A Modification method of aluminum oxide 中国石油天然气股份有限公司 2019-06-04 CN claimed
US-20180282257-A1 Aromatic Monoester Compositions and Processes for Preparing Same EXXONMOBIL CHEMICAL PATENTS INC. 2018-10-04 US claimed
CN-103739484-B The preparation method of 1,4-naphthalene dicarboxylic acids 黄石市利福达医药化工有限公司 2017-11-10 CN claimed
CN-103739484-A Preparation method of 1,4-naphthalenedicarboxylic acid HUANGSHI LIFUDA MEDICINE CHEMICAL CO LTD 2014-04-23 CN claimed
US-4748227-A Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst AMOCO CORPORATION (US) 1988-05-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180282257-A1 Aromatic Monoester Compositions and Processes for Preparing Same ADH1A, ADH1C, GK CYP1A2 88/4885NR4A1 2674/4885NR4A2 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.