Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052259 | 1.00 | CYP2D6 (0.31) | CYP2D6USP2OPRM1OPRL1GAA | |
| SCHEMBL13552065 | 0.83 | KDM4E (0.31) | — | |
| SCHEMBL1622831 | 0.80 | SMARCA4 (0.34) | — | |
| SCHEMBL1622835 | 0.80 | SMARCA4 (0.34) | — | |
| SCHEMBL710472 | 0.75 | SMARCA4 (0.31) | — | |
| SCHEMBL17893716 | 0.75 | SMARCA4 (0.31) | — | |
| SCHEMBL710471 | 0.75 | SMARCA4 (0.31) | — | |
| SCHEMBL16835509 | 0.74 | MGLL (0.35) | CYP2D6USP2ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL898593 | 0.72 | — | — | |
| SCHEMBL898594 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108827-A1 | FUSED TRICYCLIC PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-03 | — | — | WO | disclosed |