Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | PDE8B | O95263 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 4/20 | 0.40 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690893 | 0.86 | CNR1 (0.61) | CNR1ROCK1CNR2PDE8BHTR3A | |
| SCHEMBL4056691 | 0.86 | CNR1 (0.61) | CNR1ROCK1CNR2PDE8BHTR3A | |
| SCHEMBL13690929 | 0.85 | CNR1 (0.75) | CNR1ROCK1CNR2HTR3AMAPK1 | |
| SCHEMBL13691222 | 0.85 | CNR1 (0.61) | CNR1ROCK1CNR2HTR3AGUCY1A1 | |
| SCHEMBL4059909 | 0.85 | CNR1 (0.61) | CNR1ROCK1CNR2HTR3AGUCY1A1 | |
| SCHEMBL15882210 | 0.81 | ROCK1 (0.49) | CNR1ROCK1CNR2PDE8BGUCY1A1 | |
| SCHEMBL17324589 | 0.78 | ROCK1 (0.49) | CNR1ROCK1CNR2GUCY1A1GUCY1B1 | |
| SCHEMBL31429237 | 0.78 | ROCK1 (0.52) | CNR1ROCK1CNR2TSHRMAPK1 | |
| SCHEMBL15897894 | 0.78 | ROCK1 (0.52) | CNR1ROCK1CNR2TSHRMAPK1 | |
| SCHEMBL31429545 | 0.78 | ROCK1 (0.52) | CNR1ROCK1CNR2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |