Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.61 |
| ▸ | CNR2 | P34972 | 5/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | PDE8B | O95263 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690893 | 1.00 | CNR1 (0.61) | CNR1CNR2ROCK1PDE8BPIK3CD | |
| SCHEMBL13690923 | 0.86 | CNR1 (0.70) | CNR1CNR2OPRM1OPRD1OPRK1 | |
| SCHEMBL30641081 | 0.86 | CNR1 (0.70) | CNR1CNR2OPRM1OPRD1OPRK1 | |
| SCHEMBL4050989 | 0.86 | CNR1 (0.70) | CNR1CNR2OPRM1OPRD1OPRK1 | |
| SCHEMBL4052282 | 0.86 | CNR1 (0.54) | CNR1CNR2ROCK1PDE8BHTR3A | |
| SCHEMBL13690537 | 0.85 | CNR1 (0.64) | CNR1CNR2ROCK1PIK3CDPIK3CA | |
| SCHEMBL4048909 | 0.85 | CNR1 (0.64) | CNR1CNR2ROCK1PIK3CDPIK3CA | |
| SCHEMBL13690929 | 0.84 | CNR1 (0.75) | CNR1CNR2ROCK1HTR3A | |
| SCHEMBL13691222 | 0.83 | CNR1 (0.61) | CNR1CNR2ROCK1HTR3A | |
| SCHEMBL4059909 | 0.83 | CNR1 (0.61) | CNR1CNR2ROCK1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |