Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693825 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4053668 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1HPGDCYP19A1NQO2 | |
| SCHEMBL4055213 | 0.81 | MAPT (0.48) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL13693826 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4373659 | 0.76 | CYP19A1 (0.53) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2908313 | 0.73 | PDE4A (0.50) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL696497 | 0.71 | PDCD1 (0.50) | KDM4EALDH1A1KMT2AGAAHTT | |
| SCHEMBL31280042 | 0.71 | PDCD1 (0.50) | KDM4EALDH1A1KMT2AGAAHTT | |
| SCHEMBL4055500 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1HPGDCYP19A1NQO2 | |
| SCHEMBL4541903 | 0.68 | MYLK (0.40) | KDM4EALDH1A1HPGDHTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |