Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | UBE2M | P61081 | 1/20 | 0.53 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275541 | 0.91 | HPGD (0.60) | HPGDPKMHSD11B1TSHRLRRK2 | |
| SCHEMBL6279698 | 0.89 | HPGD (0.71) | HPGDPKMHSD11B1TSHRLRRK2 | |
| SCHEMBL3454519 | 0.84 | HPGD (0.69) | HPGDPKMHSD11B1TSHRUBE2M | |
| SCHEMBL17615024 | 0.84 | HPGD (0.49) | HPGDPKMHSD11B1TSHRLRRK2 | |
| SCHEMBL7299547 | 0.83 | MAPT (0.70) | HPGDPKMHSD11B1TSHRUBE2M | |
| SCHEMBL1136719 | 0.83 | L3MBTL3 (0.59) | HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL647507 | 0.82 | MGLL (0.69) | HPGDHSD11B1MGLLKMT2A | |
| Hydrochloric Acid SCHEMBL1136918 | 0.81 | L3MBTL3 (0.58) | HPGDHSD11B1MGLLKMT2A | |
| Bromide SCHEMBL1136932 | 0.81 | L3MBTL3 (0.58) | HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL13202935 | 0.81 | HPGD (0.63) | HPGDPKMHSD11B1TSHRUBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |