Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 5/20 | 0.77 |
| ▸ | MYC | P01106 | 3/20 | 0.64 |
| ▸ | MAX | P61244 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310654 | 0.88 | NAT1 (1.00) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL9427043 | 0.88 | NAT1 (1.00) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL8310652 | 0.88 | NAT1 (1.00) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL4054069 | 0.85 | NAT1 (0.77) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL4054065 | 0.85 | NAT1 (0.77) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL4058652 | 0.84 | MYC (0.63) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL4056465 | 0.83 | MYC (0.65) | NAT1MYCMAXNPC1RAB9A | |
| SCHEMBL1250155 | 0.81 | PTPN1 (0.82) | NAT1CISD1PTPN1MAOA | |
| SCHEMBL1250159 | 0.81 | PTPN1 (0.82) | NAT1CISD1PTPN1MAOA | |
| SCHEMBL4061045 | 0.81 | NAT1 (0.70) | NAT1MYCMAXNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |