Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 4/20 | 0.63 |
| ▸ | MAX | P61244 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NAT1 | P18440 | 5/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179140 | 0.93 | MYC (0.72) | MYCMAXNPC1RAB9ANAT1 | |
| SCHEMBL8179142 | 0.93 | MYC (0.72) | MYCMAXNPC1RAB9ANAT1 | |
| SCHEMBL4052864 | 0.84 | NAT1 (0.77) | MYCMAXNPC1RAB9ANAT1 | |
| SCHEMBL4056344 | 0.83 | MMP3 (0.73) | MYCMAXNPC1RAB9ACSNK2A2 | |
| SCHEMBL4056343 | 0.83 | MMP3 (0.73) | MYCMAXNPC1RAB9ACSNK2A2 | |
| SCHEMBL4058656 | 0.83 | CRHBP (0.62) | MYCMAXNPC1RAB9ANAT1 | |
| SCHEMBL4056465 | 0.82 | MYC (0.65) | MYCMAXNPC1RAB9ANAT1 | |
| SCHEMBL1250116 | 0.82 | PIM1 (0.69) | NPC1RAB9ACISD1MAOA | |
| SCHEMBL1250117 | 0.82 | PIM1 (0.69) | NPC1RAB9ACISD1MAOA | |
| SCHEMBL346694 | 0.78 | MYC (1.00) | MYCMAXNPC1RAB9ANAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |