Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 0.65 |
| ▸ | MAX | P61244 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 2/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.55 |
| ▸ | NAT1 | P18440 | 5/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958380 | 0.86 | MMP3 (0.66) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL7958378 | 0.86 | MMP3 (0.66) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL4056466 | 0.83 | CRHBP (0.61) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL7968119 | 0.83 | MMP3 (0.72) | MYCMAXNPC1RAB9ACSNK2A2 | |
| SCHEMBL7968122 | 0.83 | MMP3 (0.72) | MYCMAXNPC1RAB9ACSNK2A2 | |
| SCHEMBL4052864 | 0.83 | NAT1 (0.77) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL7972208 | 0.83 | MMP3 (0.65) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL7972211 | 0.83 | MMP3 (0.65) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL4058652 | 0.82 | MYC (0.63) | MYCMAXNPC1RAB9ACRHBP | |
| SCHEMBL4049839 | 0.80 | MMP3 (0.71) | MYCMAXNPC1RAB9ACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |