Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MAX | P61244 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 9/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052863 | 1.00 | MYC (0.46) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4053039 | 0.86 | MYC (0.56) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4053037 | 0.86 | MYC (0.56) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4057766 | 0.85 | MYC (0.57) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4057769 | 0.85 | MYC (0.57) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4050890 | 0.84 | MAPT (0.48) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4050895 | 0.83 | MYC (0.53) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4050471 | 0.80 | PTGS2 (0.51) | MYCMAXGAAMEN1KMT2A | |
| SCHEMBL4050468 | 0.80 | PTGS2 (0.51) | MYCMAXGAAMEN1KMT2A | |
| SCHEMBL4056114 | 0.78 | ADRB3 (0.36) | PTPN1MEN1KMT2AALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |