Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.57 |
| ▸ | MAX | P61244 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057769 | 1.00 | MYC (0.57) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4053037 | 0.99 | MYC (0.56) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4053039 | 0.99 | MYC (0.56) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4050895 | 0.90 | MYC (0.53) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4048268 | 0.88 | MYC (0.57) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4048271 | 0.88 | MYC (0.57) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4052863 | 0.85 | MYC (0.46) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4052867 | 0.85 | MYC (0.46) | MYCMAXPTPN1ALDH1A1MAPT | |
| SCHEMBL4051807 | 0.84 | MEN1 (0.49) | MYCMAXMAPTHPGDPOLB | |
| SCHEMBL4051802 | 0.84 | MEN1 (0.49) | MYCMAXMAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |