Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058956 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL21170007 | 0.90 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL4055273 | 0.89 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL4054016 | 0.89 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL23223734 | 0.88 | RAB9A (0.69) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL11614936 | 0.88 | RAB9A (0.69) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL4054280 | 0.86 | SMN1; SMN2 (0.75) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL13462927 | 0.86 | SMN1; SMN2 (0.75) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL16440937 | 0.86 | APP (0.56) | HRH3MAOBSENP8SENP7SENP6 | |
| SCHEMBL6142777 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |