Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.65 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 7/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | STAT5A | P42229 | 4/20 | 0.36 |
| ▸ | STAT5B | P51692 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050277 | 0.93 | TRPV4 (0.56) | TRPV4CCR1STAT6PIN1STAT5A | |
| SCHEMBL4050161 | 0.93 | TRPV4 (0.56) | TRPV4CCR1STAT6PIN1STAT5A | |
| SCHEMBL4049701 | 0.93 | TRPV4 (0.65) | TRPV4CCR1STAT6PIN1STAT5A | |
| SCHEMBL4060306 | 0.91 | TRPV4 (0.55) | TRPV4CCR1STAT6PIN1STAT5A | |
| SCHEMBL4055755 | 0.90 | TRPV4 (0.80) | TRPV4CCR1PIN1OPRM1NPY5R | |
| SCHEMBL19856867 | 0.90 | TRPV4 (0.80) | TRPV4CCR1PIN1OPRM1NPY5R | |
| SCHEMBL4056670 | 0.90 | TRPV4 (0.80) | TRPV4CCR1PIN1OPRM1NPY5R | |
| SCHEMBL4054373 | 0.90 | TRPV4 (0.80) | TRPV4CCR1PIN1OPRM1NPY5R | |
| SCHEMBL4061326 | 0.90 | TRPV4 (0.55) | TRPV4CCR1STAT6PIN1STAT5A | |
| SCHEMBL4053522 | 0.88 | TRPV4 (0.51) | TRPV4CCR1STAT6PIN1STAT5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | claimed |
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |