Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSV | O60911 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041378 | 0.95 | CTSK (0.44) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4045232 | 0.94 | CTSK (0.44) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4040706 | 0.93 | CTSK (0.45) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4039999 | 0.93 | CTSK (0.54) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4042848 | 0.93 | CTSK (0.54) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4044041 | 0.93 | CTSK (0.43) | CTSKCCR1PREPFAPKMT2A | |
| SCHEMBL4042420 | 0.93 | CTSK (0.46) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4039258 | 0.92 | CTSK (0.42) | CTSKCCR1PREPFAPCTSS | |
| SCHEMBL4051552 | 0.91 | CTSK (0.58) | CTSKCCR1CTSSCTSVCTSL | |
| SCHEMBL6235462 | 0.91 | CCR1 (0.46) | CTSKCCR1PREPFAPCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |