Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.58 |
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046358 | 0.95 | CTSK (0.54) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL4042607 | 0.94 | CTSK (0.53) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL4038859 | 0.93 | CTSK (0.53) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL4039586 | 0.93 | CTSK (0.65) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL4041699 | 0.93 | CTSK (0.56) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL4043681 | 0.93 | CTSK (0.52) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL4043273 | 0.93 | CTSK (0.65) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL4039454 | 0.92 | CTSK (0.51) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL4053232 | 0.91 | CTSK (0.48) | CTSKCTSSCCR1KMT2ACTSL | |
| SCHEMBL6209883 | 0.91 | CTSK (0.50) | CTSKCTSSCTSLCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |