Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058620 | 0.85 | LMNA (0.47) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4052162 | 0.85 | LMNA (0.47) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4050550 | 0.85 | LMNA (0.47) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4048528 | 0.84 | DHODH (0.44) | ALDH1A1MAPTLMNASTAT3ACHE | |
| SCHEMBL4061472 | 0.84 | DHODH (0.44) | ALDH1A1MAPTLMNASTAT3ACHE | |
| SCHEMBL15965560 | 0.76 | HPGD (0.44) | ALDH1A1MAPTKDM4ETDP1KEAP1 | |
| SCHEMBL8594247 | 0.74 | TDP1 (0.47) | ALDH1A1MAPTTDP1KEAP1NFE2L2 | |
| SCHEMBL8594253 | 0.74 | TDP1 (0.47) | ALDH1A1MAPTTDP1KEAP1NFE2L2 | |
| SCHEMBL4057202 | 0.72 | MEN1 (0.50) | ALDH1A1MAPTKDM4ETDP1LMNA | |
| SCHEMBL4062017 | 0.72 | MEN1 (0.50) | ALDH1A1MAPTKDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |